Saturday, May 23, 2015

Lab Grown Meat, Vertical Farms

Painter of the burial chamber of Sennedjem
Painter of the burial chamber of Sennedjem (Photo credit: Wikipedia)
For me the number one concern is cost. It has to cost less than how they do it now, much less. Or why bother?

Feeding Tomorrow’s Billions: Lab-Grown Meat Products, Vertical Farms, AI-Designed Recipes, and More
Food and agriculture accounts for about 5.9% of the global GDP. Global food retail sales alone account for about $4 trillion/year, and food accounts for 15% of what American households spend each year. .... In 1790, farm jobs accounted for 90% of US jobs, compared to less than 2% today. ...... they won't be meats in the conventional sense, but something altogether new. ...... In 2012, it took 60 billion land animals to feed 7 billion humans. If successful, cultured animal products have huge advantages: 99% less land, 96% less water, 96% fewer greenhouse gases, and 45% less energy. ........ We will increasingly rely on genetically engineered crops. In 1996, there were 1.7 million hectares of biotech crops in the world; by 2010, the number had jumped to 148 million hectares. ..... More than a trillion GE meals have been served, and not a single case of GE-induced illness has turned up. ...... Vertical farms will be immune to weather, so crops can be grown year-round under optimal conditions. One acre of skyscraper floor produces the equivalent of 10 to 20 traditional soil-based acres....... Employing clean-room technologies means no pesticides or herbicides, so there's no agricultural runoff. The fossil fuels now used for plowing, fertilizing, seeding, weeding, harvesting, and delivery are gone as well. On top of all that, we could reforest the old farmland as parkland and slow the loss of biodiversity. ....... The average American foodstuff travels 1,500 miles before it's consumed. As 70% of food's final retail price is from transportation, storage, and handling, these miles add up quickly. With vertical farming and genetic engineering, production will become decentralized and distributed, allowing food to be produced nearer the location of consumption,

and food's price to plummet

....... companies turning plants into foods that look and taste just like meat and eggs.... data scientists are actively weeding out billions of proteins from hundreds of thousands of plants to learn what could form the equivalent of a chicken's egg. ....... IBM's Watson uses machine learning to construct new recipes and cocktails that no human chef would come up with....... As technology converges, the future will be a tasty, and abundant, one.

The Laundry List From The Future



  1. A $1,000 Brain
  2. A Trillion Sensor Economy ("the Internet Of Things will create $19 trillion of newly created value")
  3. Perfect Knowledge
  4. 8 Billion Hyper Connected People ("We will grow from three to eight billion connected humans, adding five billion new consumers into the global economy. They represent tens of trillions of new dollars flowing into the global economy.")
  5. Disruption of Health Care ("$3.8 trillion healthcare industry with new business models that dematerialize, demonetize and democratize today's bureaucratic and inefficient system.....Robotic surgeons can carry out an autonomous surgical procedure perfectly (every time) for pennies on the dollar. Each of us will be able to regrow a heart, liver, lung or kidney when we need it, instead of waiting for the donor to die.")
  6. Augmented and Virtual Reality ("a new generation of displays and user interfaces....a massive disruption in a number of industries ranging from consumer retail, to real estate, education, travel, entertainment, and the fundamental ways we operate as humans.")
  7. Early Days Of JARVIS ("next-generation AI systems. In a decade, it will be normal for you to give your AI access to listen to all of your conversations, read your emails and scan your biometric data because the upside and convenience will be so immense.")
  8. Blockchain 

Friday, May 22, 2015

Reverse Brain Drain?

Best viewed large. The main terminal of the br...
Best viewed large. The main terminal of the brand new Bangalore International Airport. I was one of the first few people at the airport. My mother arrived on the third flight into this new airport. (Photo credit: Wikipedia)
Top Indian talent in Silicon Valley moves back home to join star startups
Top Indian talent is moving from globally iconic American technology companies to India's star startups. And homes are being shifted from Bay Area to Bangalore. ...... from Google to Flipkart, from Disney and Facebook to Zomato, from Symantec to Snapdeal ..... Matching dollar salaries and the sheer range of future career opportunities are the hooks India's tech blue chips are offering to Indian talent in Silicon Valley. ...... "The smart entrepreneurs have already returned, tens of thousands more will return over the next 2-3 years" ...... being wooed by at least half-adozen Indian startups valued anywhere between $1 billion and $15 billion. ...... All salaries look handsome and Silicon Valley-competitive in dollar terms, and most assignments involve complex technology solutions for the mobile platform...... startups such as Zomato, whose restaurant discovery app is now present in 22 countries, are articulating their ambitions on a global scale. For Silicon Valley's top talent, nothing attracts more than a mission to dominate the world. "The idea is always world domination, if you speak anything less than that, you are not ambitious enough. ......... Both are being paid Valley salaries too — $5-6 million annual packages. ...... but it's just a whole new level of intensity here ..... "India is at the forefront of the mobile innovation" ...... "I made the decision to move here in less than 30 seconds," said Mani. "Hundreds of millions of Indians will experience the Internet for the first time on a smartphone in the next few years" ........ "India will see a technology boom over the next 5 years that will make the US dotcom boom look lame. There will be dozens of billion-dollar companies emerging from India's ecosystem which will transform business, industry and society." ......... "History is witness to the savviest, smartest and most entrepreneurial people usually going off to crazy places at regular intervals. This is relatively reasonable"

 

Monday, May 18, 2015

Green New York


buildings could be repurposed to include vertical farms, with internal greenhouses, exterior scaffolding for hardier plants, and terraces for free-range animals. Rooftops could be covered with growing space, and solar panels could help offset the costs of keeping greenhouses warm year-round. If all of New York’s food were grown within its political limits, the city’s traffic would flow through an ocean of green. ....... discovered, unfortunately, that it would take some thirty nuclear power plants to provide enough heat and light for all those urban farms. (You need a lot of agriculture to feed eight and a half million people.) ...... how thirty per cent of New York’s consumables might be produced within a hundred-mile radius of the city ...... “Trees sequester carbon, they provide ventilation, they give shade,” he said. “We could easily lower the summer temperatures here by five degrees with more trees.”......... people fare much better, emotionally and cognitively, in greener environments than in purely urban landscapes. ....... In New York City, developments such as the High Line, the greening of Broadway, and Citi Bike are extensions of Mumford’s vision. ........ green-roofed buildings connected by tree-lined walkways.
A better idea than 30 nuclear power plants would be a city that is in tune with the Caribbean islands. Let them grow the food. It is only hours away. They do solar. Not solar heaters. Simply solar: direct Sun. More trees in the city, on the other hand, are a great idea.

The Brain

Singularity is NOT near! Stop complaining about overpopulation. Why try to mimic brains when there are so many brains out there, undernourished, underutilized?
Your brain has roughly 100 billion neurons and 100 trillion neural connections, or synapses. An iPhone 6’s A8 chip has 2 billion transistors. (Though, let’s be clear, a transistor is not anywhere near the complexity of a single synapse in the brain.) .... The highest bandwidth neural interface ever placed into a human brain, on the other hand, had just 256 electrodes. Most don’t even have that. ..... The second barrier to brain interfaces is that getting even 256 channels in generally requires invasive brain surgery, with its costs, healing time, and the very real risk that something will go wrong. .............. the former editor of the journal Neuron has pointed out that carbon nanotubes are so slender that a bundle of a million of them could be inserted into the blood stream and steered into the brain, giving us a nearly 10,000-fold increase in neural bandwidth, without any brain surgery at all.


The A16Z (AHo) Numbers

English: Mark Zuckerberg, Facebook founder and...
English: Mark Zuckerberg, Facebook founder and CEO, during his European Tour. (Photo credit: Wikipedia)

Each year, three thousand startups approach a16z with a “warm intro” from someone the firm knows. A16z invests in fifteen. Of those, at least ten will fold, three or four will prosper, and one might soar to be worth more than a billion dollars—a “unicorn,” in the local parlance.

With great luck, once a decade that unicorn will become a Google or a Facebook and return the V.C.’s money a thousand times over: the storied 1,000x. There are eight hundred and three V.C. firms in the U.S., and last year they spent forty-eight billion dollars chasing that dream........ Venture capitalists with a knack for the 1,000x know that true innovations don’t follow a pattern. The future is always stranger than we expect: mobile phones and the Internet, not flying cars. .... “The biggest outcomes come when you break your previous mental model. ...... en Horowitz, who sits next to his co-founder at the head of the table, is an astute manager who quotes the rap lyrics of his friends Nas and Kanye West to inspire fearless thinking—but he doesn’t try to manage Andreessen. ..... A16z was designed to be a full-throated argument about the future, a design predicated on its founders’ comfort with conflict. In 1996, when Horowitz was a Netscape product manager, he wrote a note to Andreessen, accusing him of prematurely revealing the company’s new strategy to a reporter. Andreessen wrote back to say that it would be Horowitz’s fault if the company failed: “Next time do the fucking interview yourself. Fuck you.” Ordinarily, relationship over. “When he feels disrespected, Marc can cut you out of his life like a cancer,” one of Andreessen’s close friends said. “But Ben and Marc fight like cats and dogs, then forget about it.” ....... He also tweets a hundred and ten times a day, inundating his three hundred and ten thousand followers with aphorisms and statistics and tweetstorm jeremiads. Andreessen says that he loves Twitter because “reporters are obsessed with it. It’s like a tube and I have loudspeakers installed in every reporting cubicle around the world.” ...... “We have this theory of nerd nation, of forty or fifty million people all over the world who believe that other nerds have more in common with them than the people in their own country. ...... Silicon Valley, the fifteen-hundred- square-mile shelf an hour south of San Francisco, was called the Santa Clara Valley until the rise of the microprocessor, in the nineteen-seventies. It remains contested ground. Armies of startups attack every incumbent, with early employees—and sometimes even their lawyers and landlords—taking deferred compensation, in the hope that their options and warrants will pay off down the line. Yet workers’ loyalty is not to a company or even to an idea but to the iterative promise of the region. “Uber is built on the efforts of thousands of people in the Valley,” the investor Naval Ravikant said. “On the back of the iPhone and Android and G.P.S. and battery technology and online credit-card payments, all stacked on themselves.”......... Apple and Microsoft got started with venture money; so did Starbucks, the Home Depot, Whole Foods Market, and JetBlue. V.C.s made their key introductions and stole from every page of Sun Tzu to help them penetrate markets. And yet V.C.s maintain a zone of embarrassed privacy around their activities. They tell strangers they’re investors, or work in technology, because, in a Valley that valorizes the entrepreneur, they don’t want to be seen as just the money. “I say I’m in the software industry,” one of the Valley’s best-known V.C.s told me. “I’m ashamed of the truth.” .......... they often follow one another, lemming-like, pursuing the latest innovation—pen-based computers, biotech, interactive television, superconductors, clean tech—off a cliff. ........ landing Sequoia, Peter Thiel, and a16z as seed investors “was a signal that was not lost on the banks we wanted to work with.” ....... The standard fee is “two and twenty”: two per cent of the fund each year, and twenty per cent of the ultimate profits. (The top firms, including a16z, charge thirty per cent.) ......... At the moment, venture funding accounts for less than 0.3 per cent of the U.S.’s G.D.P. “Venture is often called a rounding error in the economy” ....... the United States is as fossilized as Microsoft, and that the Valley has become stronger than Boston, New York, Los Angeles, and Washington, D.C., combined, Srinivasan believes that its denizens should “build an opt-in society, ultimately outside the U.S., run by technology.” ......... prescience. And then it’s removing every obstacle to the ferocious clarity of your vision: incumbents, regulations, folkways, people. Can you not just see the future but summon it? ....... A charismatic introvert, Andreessen draws people in but doesn’t really want them around. ..... has toyed with the idea of wearing a T-shirt that says “No hugging, no touching.” He doesn’t grasp the protocols of social chitchat, and prefers getting a memo to which he can e-mail a response, typing at a hundred and forty words a minute. He didn’t attend Netscape’s twentieth-anniversary celebration, because it combined two things from which he recoils: parties and reminiscing. ....... energetic and decisive, which makes him a valued counsellor. In 2006, Yahoo! offered to buy Facebook for a billion dollars, and Accel Partners, Facebook’s lead investor, urged Mark Zuckerberg to accept. Andreessen said, “Every single person involved in Facebook wanted Mark to take the Yahoo! offer. The psychological pressure they put on this twenty-two-year-old was intense. Mark and I really bonded in that period, because I told him, ‘Don’t sell, don’t sell, don’t sell!’ ” Zuckerberg told me, “Marc has this really deep belief that when companies are executing well on their vision they can have a much bigger effect on the world than people think, not just as a business but as a steward of humanity—if they have the time to execute.” He didn’t sell; Facebook is now worth two hundred and eighteen billion dollars. ......... Andreessen’s range of reference extends from Ibn Khaldun to “South Park,” yet he approaches new topics as if starved, eating through men’s fashion or whiskey-making or congressional politics until it has yielded every micronutrient. ....... He turns to theory the way a drinker turns to the minibar. ....... Horowitz also routinely forces a founder to abandon her script and regroup. It’s a stress test intended to elicit biography, resilience, and the real story...... the “idea maze”: you want the entrepreneur to have spent years thinking her idea into—and out of—every conceivable dead end ...... “we’re not funding Mother Teresa. We’re funding imperial, will-to-power people who want to crush their competition. ......... sixty-five specialists in executive talent, tech talent, market development, corporate development, and marketing. A16z maintains a network of twenty thousand contacts and brings two thousand established companies a year to its executive briefing center to meet its startups (which has produced a pipeline of deals worth three billion dollars). Andreessen told me, “We give our founders the networking superpower, hyper-accelerating someone into a fully functional C.E.O. in five years.” ...... They’ve moved into next-gen agricultural products and wearables and drone software ...... fifteen technology companies a year reach a hundred million dollars in annual revenue—and they account for ninety-eight per cent of the market capitalization of companies that go public. ....... “Deal flow is everything” ...... “I put ninety per cent of my effort into seeking out deals from the top eight venture firms, ten per cent into the next twelve, and zero per cent into all the rest.” ........ the bottom three-quarters of venture firms didn’t beat the Nasdaq for the past five years ...... “Since 1997, less cash has been returned to V.C. investors than they have invested.” ........ most V.C.s subsist entirely on fees, which they compound by raising a new fund every three years ....... V.C.s also logo shop, buying into late rounds of hot companies at high prices so they can list them on their portfolio page. ..... The tech publicist Margit Wennmachers built an eight-person marketing department and helped to orchestrate stories in Forbes and Fortune. ........ “In twenty-four months, Andreessen Horowitz was the talk of the town.” ...... house in Atherton, five minutes from a16z’s office ..... The toilet in the powder room is so visionary, and the surrounding dimmer lights so flattering, that I had to study it for some time to figure out how it flushed. ....... be aggressive and to fight your instinct to pattern-match. “Breakthrough ideas look crazy, nuts” ..... I see it in other people’s body language, and I can feel it in my own, where I sometimes feel like I don’t even care if it’s going to work, I can’t take more change.” ....... “O.K., Google, O.K., Twitter—but Airbnb? People staying in each other’s houses without there being a lot of axe murders?” .......... A16z passed on Airbnb’s A round in 2009. ..... Between 2004 and 2013, a mere 0.4 per cent of all venture investments returned at least 50x. The real mistakes aren’t the errors of commission, the companies that crash—all you can lose is your investment—but those of omission. There were good reasons that a16z passed on buying twelve per cent of Uber in 2011, including a deadline of just hours to make a decision. But the firm missed a profit, on paper, of more than three billion dollars. ................ Peter Thiel, who is four years older than Andreessen, observed that “the late nineties, for Gen Xers in Silicon Valley, was an experience as powerful as the late sixties was for the younger boomers. ....... “I always thought the entire venture thing was incredibly cool,” he told me. “Going to Kleiner Perkins”—the firm that funded Netscape—“with the high ceilings, the markers on the wall of all the great companies they’d I.P.O.’d, Larry Ellison walking through, and, at 11 A.M., the biggest buffet you’ve ever seen, at a time when I was eating at Subway? It was the closest thing to a cathedral for nerds.” Mark Zuckerberg told me, “When Marc started Andreessen Horowitz, I asked him why he didn’t start another company instead, and he said, ‘It would be like going back to kindergarten.’ ” .......... “Every firm we talk to now is ‘Hey, we’re doing all this recruiting, and we’ll introduce you to big customers.’ It’s become the table stakes.” ....... Andreessen is attempting to assuage the wound of the 2000 crash, by maintaining that it was an isolated event. “The argument in favor of concern is cyclical,” he told me—busts follow booms. “The counterargument is that stuff works now. In 2000, you had fifty million people on the Internet, and the number of smartphones was zero. Today, you have three billion Internet users and two billion smartphones. It’s Pong versus Nintendo. .......... “While Twitter is a lesser innovation than flying cars, it’s a much more valuable business. ........ Webvan was what he called a “ghost story”—a cautionary tale that still frightened investors. But Instacart proved that even haunted houses could be rehabilitated. ....... “This is an ‘I missed Uber, I don’t want to miss the next one’ climate.” ....... “Ordinary people love the iPhone, Facebook, Google Search, Airbnb, and Lyft. It’s only the intellectuals who worry.” ........ “Would the world be a better place if there were fifty Silicon Valleys?” he said. “Obviously, yes. ....... Pessimism always sounds more sophisticated than optimism ....... Software is already squeezing out other intermediaries—travel agents, financial advisers—and, at the end of the day, V.C.s are intermediaries. We’re all just selling cash.” ...... “What if we’re the most evolved dinosaur, and Naval is a bird?” ...... Already, more than half the tech companies that reached a billion-dollar valuation in the past decade were based outside Silicon Valley. ...... “Odds are, nothing your V.C. does, no matter how helpful or well-intentioned, is going to tip the balance between success and failure.” ........... “Over twenty years,” he continued, “our returns are going to come down to two or three or four investments ......... —you just don’t know which Tuesday Mark Zuckerberg is going to walk in.” ........ “Even if we could do perfect analysis, we just can’t know the future,” he said. “What if Google Ventures had access to all Google searches—could you predict hit products? Or perfect access to all of people’s conversations or purchases? You still wouldn’t know what’s going to happen. ....... If we could revise the industry completely, we’d just dump all the business plans and focus on people—the twenty-three-year-old Mark Zuckerberg, Bill Gates, Steve Jobs.” ......... “We’re imperfect people pursuing perfect ideas, and there’s tremendous frustration in the gap,” he said. “Writing code, one or two people, that’s the Platonic ideal. But when you want to impact the world you need one hundred people, then one thousand, then ten thousand—and people have all these people issues.” He examined the problem in silence. “A world of just computers wouldn’t work,” he concluded wistfully. “But a world of just people could certainly be improved.”

Robotic Surgery




Singularity might or might not happen, but what will happen along the way is pretty amazing.